Galaxy clusters are the largest gravitationally bound structures in the Universe, being completely dark matter (DM) dominated objects. Because of this, they are amongst the best targets to perform indirect DM searches. Even though they are supposedly virialized objects, they undergo different processes that act as acceleration mechanisms to produce a non-thermal population cosmic rays (CRs). According to this generally accepted scenario, galaxy clusters should shine brightly in gamma-rays, either this emission is expected from the decay of the neutral pions from the hadronic interactions of CRs protons; or from the annihilation and/or decay of DM particles. Despite the efforts in the last decades searching for this diffuse gamma-ray emission, such signal remained elusive. However, recent works strongly suggest that we may finally be on the verge of the first conclusive detection. In this talk, I will review the most recent literature on the topic and then present the results of the analysis of Fermi-LAT data searching for a DM gamma-ray signal. Finally, looking into the future, we will also discuss the prospects of the coming Cherenkov Telescope Array (CTA), to detect diffuse gamma-ray emission from the Perseus galaxy cluster.
